Identify the statement that is NOT correct (about antibody structure).

Question

Identify the statement that is NOT correct (about antibody structure).

1. A. Each antibody has two light and two heavy chains
2. B. The heavy and light chains are held together by disulfide bonds
3. C. Antigen binding site is located at C-terminal region of antibody molecules (Correct answer)
4. D. Constant region of heavy and light chains are located at C-terminus of antibody molecules

Correct Answer

Option C — Antigen binding site is located at C-terminal region of antibody molecules

Detailed Solution & Explanation

The correct answer (the incorrect statement) is Antigen binding site is located at C-terminal region of antibody molecules.

Key Points

• An antibody (H$_2$L$_2$) has two light and two heavy chains held together by disulfide bonds — statements A, B and D are correct.
• The antigen-binding site is at the N-terminal (variable) region, not the C-terminal region — so statement C is incorrect.