Match the Cytokines with Their Functions i. IL-1 - 4. Promotes inflammation, fever, and activation of T-cells

Question

Match the Cytokines with Their Functions:

i. IL-1 - 4. Promotes inflammation, fever, and activation of T-cells

ii. IL-2 - 1. Stimulates the growth of T-cells, key role in adaptive immunity

iii. IFN-gamma - 2. Activates macrophages, enhances antigen presentation, regulates immune responses

iv. TNF-alpha - 3. Plays a significant role in inflammation, immune system regulation, and apoptosis

1. A. i-4, ii-1, iii-2, iv-3 (Correct answer)
2. B. i-1, ii-2, iii-4, iv-3
3. C. i-3, ii-4, iii-1, iv-2
4. D. i-2, ii-3, iii-1, iv-4

Correct Answer

Option A — i-4, ii-1, iii-2, iv-3

Detailed Solution & Explanation

The correct answer is i-4, ii-1, iii-2, iv-3.

Key Points

• IL-1 = pro-inflammatory, fever, T-cell activation; IL-2 = T-cell growth factor (critical for adaptive immunity); IFN-gamma = macrophage activation, antigen presentation; TNF-alpha = inflammation, apoptosis.