Silencing of specific mRNA is possible via RNAi because of:

Question

Silencing of specific mRNA is possible via RNAi because of:

1. A. Complementary dsRNA (Correct answer)
2. B. Inhibitory ssRNA
3. C. Complementary tRNA
4. D. Non-complementary ssRNA

Correct Answer

Option A — Complementary dsRNA

Detailed Solution & Explanation

The correct answer is Complementary dsRNA.

Key Points

• RNA interference silences a specific mRNA because a complementary double-stranded RNA (dsRNA) binds to the target mRNA and prevents its translation.
• This mechanism is used as a cellular defence and in crop protection (e.g. against nematodes).