Which of the following co-receptors recognizes the beta2 microglobulin subunit of class I MHCs?

Question

Which of the following co-receptors recognizes the beta2 microglobulin subunit of class I MHCs?

1. A. CD24
2. B. CD4
3. C. CD8 (Correct answer)
4. D. CD16

Correct Answer

Option C — CD8

Detailed Solution & Explanation

The correct answer is CD8.

Key Points

• CD8 co-receptor on cytotoxic T cells (CTLs) recognizes MHC Class I molecules.
• CD4 co-receptor recognizes MHC Class II.
• The beta2 microglobulin is a component of MHC Class I.